DTUrtle 1.0.2

Changes

DTUrtle 1.0.1

Changes

  • filtering confusing DRIMSeq computation time messages.
  • plot_transcripts_view(): added include_ID_in_title parameter.
  • plot_proportion_barplot(): added label_angle parameter.
  • added lifecycle and R build status badges.
    • added automatic R CMD check via GitHub actions.
  • moved general package code from zzz.R to DTUrtle-package.R.
  • new Suggests: lifecycle

DTUrtle 1.0.0

Changes

  • DTUrtle manuscript got published in Bioinformatics:
    • added citation information.
    • added DOI in Readme.

DTUrtle 0.8.1

Changes

  • remodeled a lot of code - preserving functionality if not stated otherwise.
  • added basic DGE-calling methods:
  • added priming_bias_detection_probability() functionality, to estimate the potential influence of a prime-biased sequencing protocol on the DTU detection ability.
  • added Vignettes for a Smart-seq2 single-cell data set from Wuidart et al.
  • Vignettes: added sections showcasing DGE calling and priming bias detection probability calculation.
  • new Dependency: DESeq2
  • new Suggests: glmGamPoi, apeglm

DTUrtle 0.7.4

Changes

  • plot_transcripts_view(): added tested_transcripts_only parameter, to allow better control which transcripts of a gene should be displayed. Also allows to create plot for genes which have been excluded from the analysis.
  • plot_transcripts_view(): changed default value of reduce_introns_fill to ‘white’ to get visually more appealing plots by default.

DTUrtle 0.7.3

Changes

  • readded “GenomicFeatures” as dependency - eases installation.
  • measure and show computation time in vignettes.
  • extended vignettes.
  • extended README.
  • plot_proportion_barplot(): define data and mapping already in general ggplot function, to ease editability.
  • plot_proportion_barplot(): added global ‘text_size’ parameter.
  • plot_dimensional_reduction(): added ‘plot_scale’ parameter, allowing for free x- or y-axis of facets, or both.
  • plot_dimensional_reduction(): added global ‘text_size’ parameter.
  • plot_transcripts_view(): added ‘arrow_start’ parameter, to allow adjustment of the transcript annotation start position.
  • plot_transcripts_view(): changed default parameters and resolution, to get visually more appealing high quality plots.
  • import_gtf(): generalized function and added parameter for returned feature type and return format. Now can create fitting plot_transcripts_view() GTF input.
  • run_drimseq(): added susbet_feature and subset_sample parameters, replacing subset_counts. Now samples and features can be excluded from analysis on the fly.
  • run_drimseq(): added add_pseudocount parameter, to enable comparisons of features with zero expression in one comparison group.
  • run_drimseq(): added filter_only parameter, to return (sparse) count matrix after group-based filtering.
  • combine_to_matrix(): added ability to infer Seurat cellname extension.
  • removed dependency of ‘stringi’.
  • added ‘sparseDRIMSeq’ to depending packages, to get rid of sometimes not-occurring package load.
  • fixed some smaller bugs.

DTUrtle 0.7.1

Changes

  • add new vignette for Tabula Muris (Mouse) data set.
  • combine_to_matrix(): added cell_extension_side parameter to choose label append or prepend.
  • plot_dimensional_reduction(): added functionality to plot in dimensional reduction space.
  • plot_transcripts_view(): safer and more specific IdeoGram track generation.
  • plot_transcripts_view(): improved handling of non-UCSC chromosome identifiers.
  • run_drimseq(): added check for matching names of counts and tx2gene.
  • run_drimseq(): added subset_counts parameter - ability to force subset the count matrix to matching tx2gene features only.
  • plot_dtu_table(): disable warning for server side rendering.
  • plot_proportion_pheatmap(): plots names are now run through make.names(), as all other plots.
  • create_dtu_table(): changed default column names and added description of column meaning.
  • extended checks for provided file paths.
  • safer BiocParallel starting and stopping.
  • made whole package documentation searchable via docsearch.
  • README: fixed typo and added link to vignettes.
  • set GenomeInfoDb as standard Imports.
  • minor improvements.

DTUrtle 0.2.6

Changes

  • add add_to_table parameter to plotting functions, to add plot savepaths directly to dtu_table.
  • run_drimseq(): added description of predefined filter strategies.
  • run_drimseq(): added check if two sample groups are left after excluding unused samples.
  • minor update of function documentation.
  • plot_dtu_table(): add min_page_length parameter.
  • plot_dtu_table(): slightly change icon and heading alignment.
  • added conditional vignette evaluation.
  • added knitr in Suggests for vignette building.

DTUrtle 0.2.5

Changes

  • initial first version.